What Are the 10 Safest Cities in South America in 2025?
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I’ve spent large chunks of the last 3 years in South America, visiting almost every country on the continent (only Venezuela to go) and going to just about every major area of interest.
I was shocked to find that there are lists of the safest cities in South America that rank dangerous places fairly high up the list.
Colombia’s Medellin was once the most dangerous city in the world during Pablo Escobar’s heyday in the early 1990s. That’s no longer the case, but with druggings and robberies still rife, it’s absolutely not one of the safest cities in Colombia, let alone South America.
Uruguay’s beach city Punta del Este is fairly safe, but it becomes a ghost town when summer is over and criminals swarm in to rob properties en masse. Whilst Santiago, Chile, is a hotspot for rioting.
Some of the safest cities on the continent don’t even get a mention. The likes of Ushuaia and Colonia del Sacramento are some of the safest places in the Americas. Yet large websites that write “top 10” lists tend to pump out poorly researched content coming from writers who have little or no experience of the subject.
I want you to know what it’s really like down here, and where you can really go to relax without worrying too much about safety.
I’ve been to every city on this list, I’ve met locals who live in these places, and can tell you from first-hand experience, that they’re the safest spots to visit on this beautiful continent.
The Safest Cities in South America to Visit in 2025
1) Ushuaia, Argentina
Top of the list is Ushuaia on the southern tip of Argentina. Argentina is Latin America’s safest country and Ushuaia is Argentina’s safest city.
It’s the perfect place to start if you’re visiting South America for the first time.
Argentina is a country the size of a continent. The distance between Ushuaia and capital Buenos Aires is similar to that between London and Athens: around 3,000km or almost 2,000 miles.
And Buenos Aires is just about the nearest spot with any real crime issues at all.
Ushuaia is a rarity in South America, the windows don’t have bars on them.
Coming from Europe, I was shocked when I first came to this part of the world a few years ago and saw barred-up windows pretty much everywhere, as if most cities were really just giant prisons.
Not in Ushuaia however. This city on Tierra del Fuego island is cut off from the rest of Argentina, as you have to pass through Chile to reach the mainland. Aside from the language and some food similarities, Ushuaia feels like a different country compared to northern hotspots including Salta, Buenos Aires and Iguazu Falls.
Ushuaia scores low or very low for most crimes, and even scores “highly” for safety whilst walking alone at night. And I walked away from the city with my girlfriend after dark. The walk was an hour long, and we never felt remotely close to danger. Only a little cold!
Speaking of cold, that’s the one thing you do have to worry about here. This Patagonian winter wonderland is freezing in the winter time (June-August) so you need to wrap up warm.
Take particular care whilst hiking in the winter throughout the likes of Tierra del Fuego National Park and Martial Glacier. Go with a guide if you aren’t used to trekking in harsh conditions.
And keep an eye on the weather forecast before you do a Beagle Channel tour. The waters can get a little choppy.
Otherwise, come and enjoy Ushuaia’s many highlights. This isn’t just a safe city, it’s also one of the best in South America. A winning situation all round.
2) Colonia del Sacramento, Uruguay
Argentina is Latin America’s safest country these days, both statistically, and in terms of what I’ve experienced first-hand visiting most South American cities of note.
The country it knocked off top spot however, is Uruguay. And the gateway city of Colonia which you can easily reach from Buenos Aires, is a super safe spot to visit.
This sleepy Uruguayan border city is easily visitable on a day trip from Buenos Aires. However you may want to give it a little more time if you feel like slowing things down a little.
To be honest, a day is all you need here. I stayed for two nights on my first visit, and that was too long. I took a day trip from the Argentinian capital with my girlfriend two years later, and we saw everything we wanted to in Colonia.
It’s a slow-paced location with quaint colonial buildings. It doesn’t feel like a city at all with its lack of towering skyscrapers and hustle and bustle culture which you’d associate with city life.
Crime here is very low. It has a bit of a retirement village vibe. Some lovely cafes and restaurants, a handful of beaches, and an all-round chilled feel.
Super safe and there’s just about nothing to worry about here.
3) Bariloche, Argentina
We started our 2-week Patagonia adventure in one of the safest cities in the Americas (Ushuaia), and ended it in another one (Bariloche).
Bariloche is just about as European as it gets in South America. Cold weather? Tick. Alpine-style buildings? Tick. Great chocolate? Tick. And we ate far too much of the latter during our visit here… but we certainly don’t regret it.
This city is known for two things: its amazing chocolate, and its incredible scenery, which is also very reminiscent of Europe.
And the best thing is, it’s super safe.
Bariloche is a perfect example of why I wrote this guide. There’s so much inaccurate information online, including these stats which portray Bariloche as dangerous.
Well, it’s not. Speak to anyone who’s been there, speak to locals, ask questions in Facebook groups on Argentina, Patagonia and South America travel. I guarantee no one will tell you it’s a dodgy city.
Bariloche’s stunning lake and mountain scenery reminded me of Lake Bled in Slovenia. And the safety levels felt similar to Slovenia too.
Crime here is low, and it’s perfectly fine to walk alone at night here, something I wouldn’t recommend in 90% of Latin American cities.
The downtown area is busy at all hours, so you don’t need to be worrying about it turning into a spooky ghost town after dark.
As with Ushuaia, the main dangers here are cold weather and mountainous terrain. Not crime. Bariloche is another reason why Argentina is very safe.
4) Mendoza, Argentina
Mendoza is one of my favourite cities in the world. It has lovely parks, you can order world class Argentinian steak, the climate is good, and as you can perhaps tell from its inclusion on this list, it’s very safe.
Mendoza is the next major city if you head north from Bariloche, and the safest in Argentina outside of Patagonia.
Mendoza is great. It’s famous for its wine, and it also works as a base city to visit South America’s highest mountain, Aconcagua.
But we’re here to talk about safety, and as with every city in this list, crime is low. Mendoza is another example of why I write this guide. Because the information available online is wildly inaccurate and makes it sound like a dodgy place.
It’s not.
I’ve been here twice now, and if I could choose one place in South America to live, it would be Mendoza.
Even at night time, we walked many times from the centre to our apartment 30 minutes away with no issues. It did feel a little eerie at times with no other people around, but it never felt dangerous.
And locals tell us the same, you don’t have to worry about crime in Mendoza, assuming you take basic precautions and don’t walk around the streets with your phone out. That’s a no-no in almost any Latin American city (I would say Ushuaia and Colonia are the only exceptions).
The only real danger in Mendoza, is that they have massive ditches alongside the paths. If you aren’t careful or you have a few too many glasses of the local wine, it would be easy to fall into one of these and injure yourself.
I guess the plus side is that they are so big, you can’t really miss them.
Otherwise, Mendoza is a great place to chill and live away from the dangers that other parts of South America bring.
I love it here, and I’m sure you will too.
5) Arequipa, Peru
Arequipa is one of the most scenic cities in South America, and it’s also very safe.
Peru is a mixed bag overall. Some parts of the country, like the notorious mining town of La Rinconada, can be very dangerous. Others on the other hand, are very safe, just like Arequipa.
You don’t have much to worry about here, especially if you dress down and keep your phone in your pocket (once again, pretty standard Latin American safety tips).
The only problem I have heard coming from this city, is that taxi drivers (street taxis, not Uber which works here) have been known to scam and rob passengers. Unfortunately this is an issue in many countries worldwide. I never use street taxis where possible.
Stay around the Plaza de Armas and you should be fine. This is the main tourist square. Pickpockets often operate in touristy areas like this. They aren’t a major threat in Arequipa, but that doesn’t mean they’re non-existent.
One slightly worrying moment came when my phone started blaring out a loud alarm noise I’d never heard before. It turns out this was an earthquake alarm and there was an active earthquake taking place at that very moment.
Now I never felt anything, but it turns out Peru is susceptible to earthquakes. There hasn’t been a major earthquake (10+ deaths) since 2007. You can read Peru’s earthquake stats for reassurance on how rare they are. And in Arequipa they’re even rarer.
So don’t be scared off by the tiny threat of natural disasters.
Otherwise, this beautiful city is the main gateway to Colca Canyon, where you will need to apply mountain safety tips. But in Arequipa itself, there’s little to worry about.
Make sure you put this city on your Peru itinerary.
6) Cusco, Peru
Another super safe spot in Peru is Cusco, by far the most popular city for foreign tourists. This is the gateway to Machu Picchu. It is also a great base for other awesome spots such as Mount Vinicunca (Rainbow Mountain) and the Sacred Valley.
If you hang around the city centre, there’s often a large police presence there. They know this place is super touristy, and the last thing they want is for something terrible to happen to a visitor, as Cusco relies heavily on tourists to boost its economy.
There are generally lots of people around the centre at all hours.
The one drawback of Cusco being so touristy, is that you do have to be wary of little tourist scams and attempts to rip you off. Someone may ask if you want a photo with their alpaca for example, then demand you pay the equivalent of a few US dollars for it.
Cusco’s main danger comes from high altitude. It is 3,400 metres (over 11,000 ft) above sea level. Which means altitude sickness is a real possibility here. And whilst I didn’t get ill here, I had altitude sickness in the Bolivian altiplano, and it was a really unpleasant experience.
The trick is to acclimatise. You should spend 2-3 days here taking it easy and not doing any major activities. After that you can start looking into mountain hikes including Rainbow Mountain and Machu Picchu.
Once again though, Cusco is very safe. Even if you do nothing else in Peru, this city (including the surrounding mountains) should be an essential part of your South America travel route.
7) Aregua, Paraguay
The 7th of our safest cities in South America for tourists and expats alike is Aregua in Paraguay.
Now if you plan on visiting South America’s most underrated country, you can read all about safety in Paraguay first. A country I’ve been to several times.
Aregua is a very easy day trip from the capital Asuncion. Whilst I’ve been to Asuncion several times and felt little danger there, Aregua has a much more laid back feel to the place.
There are several cool things to do in Aregua which include chilling by the beach and taking a boat ride across Lake Ypacarai.
One common trend is that smaller, more laidback cities tend to be safer than bustling metropolises. And that’s definitely the case in slow-paced Aregua.
We enjoy coming here in mid-to-late winter for the annual strawberry expo which takes place (usually) from July-September.
Don’t expect any bucket list activities like Machu Picchu or Patagonia round here. But do consider putting Aregua on your Paraguay itinerary if you want to slow down for a bit and relax in one of South America’s safer spots.
The only hazard you should be aware of, is that Lake Ypacarai is heavily polluted, and you should not attempt to swim in it. Take a boat ride instead.
8) Montevideo, Uruguay
Admittedly Uruguay is one of the most boring countries in South America, but it’s also one of the safest.
Montevideo isn’t quite as safe as Colonia, but it’s still a city with a fairly low threat level compared to most South American cities.
In fact, Montevideo is just about the safest capital city in South America. Only Sucre (Bolivia) really runs it close, with Buenos Aires (Argentina) not far behind.
The only part that most locals and travellers warn against walking in alone at night, is the Ciudad Vieja area, which is where the historic centre is based.
To be honest, I walked alone at night around Ciudad Vieja several times during my two weeks in Montevideo, and whilst there were a few dodgy characters around, I didn’t feel in imminent danger.
I would say that you should probably err on the side of caution and not copy me here. Aside from the local supermarket, pretty much everything shut down, and the alcoholics and drug addicts take over this part of Montevideo until sunrise when it becomes very safe again.
I won’t pretend Montevideo is a fun city. But it is a very safe one. Uruguay attracts more business travellers with its favourable taxation laws rather than tourists.
Uruguay has a lot of similarities with Argentina in terms of food and European-style architecture and culture, but none of the magical landscapes its neighbour has.
If we compare the two capitals however, Montevideo is safer than Buenos Aires. The security situation in the Uruguayan city is better overall than in Argentina’s popular capital which has more extremes between the good parts and the bad.
9) Salta, Argentina
Our fourth and final entry in this list from Argentina is Salta, a city in the northwest which has more of an Andean/Peruvian vibe than a feel similar to Mendoza, Buenos Aires or Argentine Patagonia.
It shouldn’t surprise you that Argentina dominates this list. According to the Global Peace Index, it’s the safest country in South America, the 2nd-safest in all the Americas (behind Canada) and the 47th-safest worldwide, just behind ultra safe South Korea (where I used to live) in 46th.
In Salta, you should be a little wary around the bus station after dark. And pickpockets do operate in the city, so be careful, especially around the tourist centre of Plaza 9 de Julio.
Otherwise however, that’s as bad as it gets.
We had an Airbnb right in the plaza, and we were told off for locking the door at night as the owner said it should be unlocked at all times.
Not really a smart thing to do. But when the door was unlocked, you could literally push it open. And when the owner feels its safe enough to leave like that at all hours, it speaks volumes about the safety situation in Salta.
In case you’re wondering, we were at least allowed to lock our room. So it wasn’t like people could walk directly from the street to our bedroom unhindered.
Salta is a fun city, with nearby attractions including Cafayate (famous for its delicious alfajores) and the Salinas Grandes, a series of cool salt flats.
It’s also easy to get to Uyuni in Bolivia from here. And that’s a serious bucket list destination. So I’d recommend tagging that onto your trip if possible.
10) Baños, Ecuador
This may raise a few eyebrows, because Ecuador is not very safe right now. Gang wars have made the likes of Guayaquil and much of the Pacific coast almost no-go zones, whilst capital Quito is a city where I was almost mugged.
The good news, is that Baños is a little oasis within this troubled nation.
Baños is the adventure sports capital of Ecuador, so you come here for hiking, bungee jumping, white-water rafting and more activities that will get the adrenaline pumping.
As a tourist spot, it’s a little more secure here. That doesn’t mean that it’s completely crime-free. It isn’t. But it’s still safer than most South American cities, and a lot safer than most Ecuadorian cities.
Once again, take standard Latin America safety precautions (hide your valuables and don’t go out at night). I would say that chances are you will be fine after dark here. But unlike other cities on this list, I wouldn’t say that it’s almost certainly going to be fine.
Be careful with some of the hikes and adventure activities here. Of course, accidents can happen, and sometimes your travel insurance won’t cover adventure sports. So make sure you are covered just in case something goes wrong.
Honourable Mentions
Some cities just fell short of this list. One of the biggest omissions is Buenos Aires. The capital of Argentina is mostly very safe, but it does have its danger spots.
The famous La Boca neighbourhood is safe during the day, but at night and in the surrounding areas (both day and night) it is one of the few real danger spots in Argentina.
Another Argentinian city, Cordoba could also have been mentioned. It may well have been if I expanded this top 10 to a top 11.
There are several really fun small towns dotted around South America. Barichara and Guane in Colombia and Brazil’s Gramado and Canela are some of my favourites. They’re all super safe, despite being in countries which overall have a higher risk level. But this list is on cities, so they don’t make the cut.
El Calafate in Argentine Patagonia is also super safe. It’s the main gateway to magical bucket list locations including Perito Moreno Glacier and Torres del Paine just across the border in Chile. Yet once again, it’s a town so it doesn’t meet the criteria for this list.
Why Have Other Well-Known “Safe” South American Cities Not Made This List?
There are some other cities which often make “safest South America city” lists, which I intentionally haven’t included here. Let me explain why.
Punta del Este in Uruguay is one such example. This popular beach destination is super safe during the summer. However in winter time, it becomes a bit of a ghost town and locals talk of a high crime wave as criminals loot properties whilst many residents stay away.
It’s very safe during the summer though.
Florianopolis is often named as one of the safest cities in Brazil. We didn’t feel that way though. We spotted a fair few shady characters in the city centre even in broad daylight. We felt unsafe there and quickly left.
We also heard a gunshot one night outside our accommodation. We stayed in two places on a large hill which the city is built around, and they felt like Brazil’s notorious favelas.
Florianopolis is far safer than Sao Paulo or Rio de Janeiro (a city with loads of cool things to do by the way), but I certainly wouldn’t consider it “safe safe”.
Outdated information also claims that Santiago in Chile is safe. This is based off Chile’s reputation as a very safe country. And whilst that’s true for much of Chile, it’s not for Santiago.
The capital is home to regular riots where protestors attack riot police, who respond with strong force. I was tear gassed when one of these riots took place outside my hostel. They are more regular occurrences on Friday afternoons.
Another thing I noted in Santiago, is how most buildings are barricaded up with not just barred windows (like many South American cities), but also large sheets of metal which turn business into impenetrable fortresses when they’re closed for the night.
Something I haven’t seen elsewhere in South America, even in the dodgier places.
I’ve also seen Medellin in Colombia ranked as a “safe city”. It’s not.
Sure, nothing happened to me when I was there, but a lot of tourists do run into trouble. It’s especially notorious for criminals spiking tourists’ drinks with scopolamine and robbing them whilst unconscious. In the worst cases, tourists have been killed from these incidents including 39 in 2024.
Will I Definitely be Safe if I Only Visit Cities on This List?
No. You can never guarantee safety, even in the safest places in the world. I don’t say this to scare you, it’s just a fact.
You can spend a day walking through the most dangerous regions of Mali and have nothing happen to you, then spend a day in Singapore and get mugged.
Of course the odds of those occurrences are low, but the chances of facing danger are never zero, even in your home town.
South America is a beautiful part of the world. And I would love you to come down and enjoy this continent as much as I do.
As long as you follow the safety advice I wrote in this guide, you have a very low chance of being harmed, even in places more dangerous than those on this list.
Stay safe, and happy travels!
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